This classic Florida barrier island is accessible only by boat, but it is worth the ride. A boardwalk takes visitors across mangrove forests and hammocks of live oaks, cabbage palms, paradise trees, and wild limes to a neatly preserved Atlantic beach. During the summer months, the island is an important nesting area for loggerhead, leatherback, and green turtles. They come ashore at night to dig holes in the beach sand where they lay their eggs. The preserve is a favorite for nature students interested in learning about the native flora and fauna of Florida barrier islands. Visitors come to swim, sunbathe, or picnic at the pavilion on the quiet beach. Others make the trip for the great surf fishing. Snorkeling and scuba diving are also popular activities. Located at Port Salerno, on the Intracoastal Waterway, 2/3 of a mile south of the inlet.

Many species of wildlife may be observed at St. Lucie Inlet Preserve State Park, including bobcats, otters, raccoons and more. Morning and late afternoon are the best times to see most wildlife, since it is when they are feeding and most active. The park's varied habitats provide excellent opportunities for birding enthusiasts to view many different species of birdlife. The park is part of the Great Florida Birding Trail. St. Lucie is also a very good place to see wading birds and shorebirds including Great Blue Herons, Brown Pelicans, White Ibis and the Purple Plover.

The water temperature varies from the mid to upper eighties in the summer, to mid to lower seventies in the winter. Riptides can occur on days with strong onshore winds. There are no lifeguards on duty.

Although no rentals are available, there are miles of tidal creek waiting to be explored with your own kayak or canoe.